What we want to achieve
A comprehensive dataset describing the nutritional status of pregnant South Asian women and the effect this has on their offspring will be realised. This knowledge, when combined with that from the trial interventions, which are designed to assess whether it is possible to correct nutritional deficiencies during pregnancy, will inform the design of a robust, pragmatic intervention aimed at diabetes prevention in pregnancy.
The quantitative result of WP2 and WP3 will be used in the context of qualitative results from WP9 and WP10. These work packages will provide an insight into the views of South Asian women in relation to accessing antenatal care in Europe and diabetes in pregnancy. Incorporating what is learnt from this qualitative research will give the intervention the maximum possibility of being not only effective, but also meeting the needs of the target population, and being successful in a real-world environment.
The planned health economic analysis will assess the affordability of this intervention, in both Europe and South Asia. This will facilitate influencing public health policy to introduce recommendations arising from this research.
The genetic and epigenetic information gained will improve understanding in the field of gene-environment interaction and may give rise to the possibility of this being used in a clinical setting.
Stakeholders in diabetes prevention will be able to learn about results of the GIFTS programme through dissemination of information. This will take the form of the website, peer-reviewed publications and the development of an e-learning portal. In addition, existing diabetes prevention curriculums will be revised.
We will publish the results of the Project here. You can keep up to date with our progress with the Newsletters in the Media Centre and our periodic reports.
- Greenhalgh T, Clinch M, Afsar N, Choudhhury Y, Sudra R, Campbell-Richards D, Claydon A, Hitman G, Hanson P, Finer S: Socio-cultural influences on the behaviour of South Asian women with diabetes in pregnancy: qualitative study using a multi-level theoretical approach. BMC Medicine 2015, 13:120.
- Rayanagoudar G, Hashi AA, Zamora J, Khan KS, Hitman GA, Thangaratinam. Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women. S.Diabetologia. 2016 Jul;59(7):1403-11.